New PDF release: Alzheimer's Disease (Genes & Disease)

By Evelyn B Kelly

ISBN-10: 0791095886

ISBN-13: 9780791095881

ISBN-10: 1438118112

ISBN-13: 9781438118116

Alzheimer's affliction is the commonest kind of dementia in older adults, robbing them in their minds and dignity. offering a historical past of the , this name appears on the human genome and explores how the items of the Alzheimer's puzzle are commencing to healthy jointly.

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Extra resources for Alzheimer's Disease (Genes & Disease)

Sample text

As we have seen, genes are sequences of DNA. Sequencing hunts for those genes and finds their places on chromosomes. in57 57 8/21/08 4:48:26 PM 58 Alzheimer’s Disease on all of the human chromosomes. Sequencing is done with powerful computers. After a possible sequence is found, it is stored in a database. Computers then scan thousands of entries comparing the same gene in different species. Three techniques are used to develop other information about AD: transgenic animals, twin studies, and quantitative trait loci (QTL).

Sequencing hunts for those genes and finds their places on chromosomes. in57 57 8/21/08 4:48:26 PM 58 Alzheimer’s Disease on all of the human chromosomes. Sequencing is done with powerful computers. After a possible sequence is found, it is stored in a database. Computers then scan thousands of entries comparing the same gene in different species. Three techniques are used to develop other information about AD: transgenic animals, twin studies, and quantitative trait loci (QTL). Transgenic Animals Researchers have been able to create animals that have symptoms of Alzheimer’s.

Scientists have studied the chemical structure of these proteins. Finding the genes that are responsible for making the proteins has been a task that rivals any detective story. 2 Positron emission tomography (PET) scans show the metabolic activity in a normal brain (a) compared to the decline in metabolic activity shown in a brain with Alzheimer’s disease (b). RUDOLPH TANZI: DECODER OF DARKNESS Rudolph Tanzi traveled along a Boston street on a cloudy September day in 1980. As a college graduate with degrees in both microbiology and history, he had heard of an opening in the laboratory of James Gusella at Harvard University.

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Alzheimer's Disease (Genes & Disease) by Evelyn B Kelly


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